2022-23 Potential Projects: Infectious Disease

Supervisors Project Title Cross Institutional Supervision Theme/s Keywords
Kaja Abbas &
Kim Mulholland
Health and economic impact modelling of cervical cancer elimination strategies at the global and national levels No Global Health
Health Data Science
Infectious Disease
Human papillomavirus vaccine;
Cervical cancer elimination;
Infectious disease modelling;
Cost-effectiveness analysis
Mark Bodman-Smith &
Elisabetta Groppelli &
Javier Salguero Bodes &
Sally Sharpe
An ‘unconventional’ approach to the COVID 19 pandemic: the role of gamma delta T cells in virus recognition No Global Health
Infectious Disease
Non-conventional T cells;
SARS-CoV-2;
Trained innate immunity;
in vitro investigation of ex vivo pathology
Amaya Bustinduy &
Sanjeev Krishna &
Bonnie Webster
Development, implementation and assessment of isothermal point-of-care molecular diagnostics for both Female Genital Schistosomiasis and Human Papillomavirus Yes Global Health
Translational Implementation Research
Infectious Disease
FGS;
HPV;
Diagnostics;
Isothermal
Sam Clifford & Stephane Hue & Liz Miller Inferring SARS-CoV-2 transmission and its direction from viral genomics and mathematical inference No Health Data Science
Infectious Disease
SARS-CoV-2; Transmission chain reconstruction; Bayesian statistical inference; Viral genomes; Phylodynamics
Stefan Flasche &
Bhargavi Rao &
Kevin Van Zandvoort
Modelling the effectiveness of antibiotic mass administration in acute humanitarian crises No Global Health
Health Data Science
Infectious Disease
Humanitarian crises;
Antibiotics;
Antimicrobial resistance;
S pneumonia;
Modelling
Nick Furnham &
David Allen
Developing machine learning tools to investigate evolutionary trajectories in emerging viral infectious diseases No Health Data Science
Infectious Disease
Molecular virology;
Sars-CoV-2;
Structural bioinformatics;
Machine learning;
Host-pathogen interactions;
Emerging infections
Ozan Gundogdu &
Brendan Wren
Campylobacter pathogenesis: Investigating the link between the Unfolded Protein Response and inflammation No Infectious Disease Campylobacter;
Gastroenteritis;
Diarrhoea;
Unfolded Protein Response (UPR)
Rein Houben &
Nicky McCreesh
Impact of inter-community transmission on reductions in tuberculosis incidence achieved through interventions: mathematical modelling No Global Health
Infectious Disease
Tuberculosis;
Social contact;
Mathematical modelling;
South Africa
Sanjeev Krishna & Quinxue Hu Development and implementation of highly sensitive SARS-CoV-2-specific immunodiagnostics for rapid and high throughput screening No Translational and Implementation Research
Infectious Disease
COVID-19; SARS-CoV-2; Unitope design;
Single domain antibody;
Point-of-care immune diagnostics
Jodi Lindsay &
Gwen Knight &
Kat Holt
Transfer and stability of antimicrobial resistance (AMR) genes in Methicillin-Resistant Staphylococcus aureus (MRSA) Yes Global Health
Translational and Implementation Research
Infectious Disease
Antimicrobial resistance;
Microbiology;
Molecular biology;
Bioinformatics;
Mathematical modelling
Nicky McCreesh & Richard White Improving model projections of intervention impact through investigating the effects of choices made in the design and analysis of social contact surveys No Global Health
Infectious Disease
Social contact; Mathematical modelling; COVID-19; Airborne transmission
Finn McQuaid &
Gwen Knight
Comparing drug-resistant tuberculosis treatment choices No Global Health
Infectious Disease
Tuberculosis;
Drug-resistance;
Modelling;
Health Economics;
Empiric antibiotic use
Julia Moreira Pescarini & Enny Cruz & Lizzy Brickley Targeting persistent health inequalities in infectious diseases in Brazil: An intersectional approach No Global Health
Health Data Science
Infectious Disease
Leprosy; Tuberculosis; HIV; Intersectionality; Health equity; Big data
Kath O’Reilly &
Henry Staines
Using Wastewater Based Epidemiology (WBE) to Support Public Health Yes Global Health
Health Data Science
Translational and Implementation Research
Infectious Disease
Data science;
Modelling;
Policy;
Infectious diseases;
PCR
Rajko Reljic &
Graham Bothamley
Antibody and aptamer approach to diagnosis of TB based on secreted proteins of Mycobacterium tuberculosis Yes Translational and Implementation Research
Infectious Disease
Tuberculosis;
Diagnosis;
Serology;
Aptamers;
Latent infection
Blair Strang &
Steve Goodbourn
Viral evasion of innate immunity: have we misunderstood one of the world’s most widespread viruses? No Infectious Disease Anti-viral immunity;
Human cytomegalovirus;
Interferon
Cally Tann &
Kirsty Le Doare &
Eric Ohuma &
Joy Lawn
Intrapartum-related neonatal encephalopathy in Africa: Defining burden, risk and outcomes Yes Global Health
Health Data Science
Translational and Implementation Research
Infectious Disease
Newborn;
Neonatal encephalopathy;
Risk score;
Global estimates
Damien Tully &
Deogratius Ssemwanga &
Pontiano Kaleebu
Development of novel approaches for HIV drug resistance detection using nanopore sequencing technology No Global Health
Infectious Disease
HIV;
Drug resistance;
Genomics;
Public Health;
Molecular epidemiology;
Evolution
Richard White &
Christinah Mukandavire &
Chathika Weerasuriya
Creating evidence for novel Tuberculosis vaccine introduction and implementation decision making – using math modelling No Global Health
Infectious Diseases
Mathematical modelling;
Tuberculosis;
Vaccines
Laith Yakob &
Timothy Planche
Modelling Clostridium difficile vaccination strategy for the UK Yes Global Health
Health Data Science
Translational and Implementation Research
Infectious Disease
Mathematical modelling;
Computational biology;
Infectious diseases;
Epidemiology;
Vaccination;
C. difficile

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