2022-23 Potential Projects: Translational & Implementation Research

Supervisors Project Title Cross Institutional Supervision Theme/s Keywords
Thomas Barrick &
Franklyn Howe &
Matt Hall &
Philip Benjamin		 Development of clinically specific tissue microstructural biomarkers from quasi-diffusion imaging No Translational and Implementation Research Magnetic Resonance Imaging;
Quantitative Imaging;
Quasi-Diffusion Imaging;
Neuroimaging;
Diffusion Dynamical Modelling;
Tissue Microstructural Modelling
Amaya Bustinduy &
Sanjeev Krishna &
Bonnie Webster		 Development, implementation and assessment of isothermal point-of-care molecular diagnostics for both Female Genital Schistosomiasis and Human Papillomavirus Yes Global Health
Translational Implementation Research
Infectious Disease		 FGS;
HPV;
Diagnostics;
Isothermal
Christopher Carroll &Alan Pittman Development of a transgenic mouse model for preclinical studies of therapeutic testing of mitochondrial disorders No Translational and Implementation Research Omics;
Metabolism;
Inherited metabolic disease;
Transgenics
Franklyn Howe &
Thomas Barrick &
Philip Benjamin		 MRI tractomics of glial brain tumours No Translational and Implementation Research Magnetic resonance imaging (MRI);
Brain tumour;
Machine learning;
Quasi-Diffusion Imaging (QDI)
Sanjay Kinra &
Salina Ahmed		 Improving the effectiveness of diabetes self-management education and behavioural support in Thailand, India, and Uganda No Translational and Implementation Research
Health Data Science
Global Health		 Diabetes self-management education;
Evaluation of complex interventions;
Behavioural interventions;
Data science;
Interdisciplinary research;
Global health
Sanjeev Krishna & Qinxue Hu Development and implementation of highly sensitive SARS-CoV-2-specific immunodiagnostics for rapid and high throughput screening No Translational and Implementation Research
Infectious Disease		 COVID-19; SARS-CoV-2; Unitope design; Single domain antibody;
Point-of-care immune diagnostics
Kirsty Le Doare &
Janet Seeley		 Improving informed consent for clinical vaccine trials in pregnant women in Uganda Yes Global Health
Translational and Implementation Research		 Vaccination;
Pregnancy;
Children;
Hesitancy;
Clinical trial
Jodi Lindsay &
Gwen Knight &
Kat Holt		 Transfer and stability of antimicrobial resistance (AMR) genes in Methicillin-Resistant Staphylococcus aureus (MRSA) Yes Global Health
Translational and Implementation Research
Infectious Disease		 Antimicrobial resistance;
Microbiology;
Molecular biology;
Bioinformatics;
Mathematical modelling
Kath O’Reilly &
Henry Staines		 Using Wastewater Based Epidemiology (WBE) to Support Public Health Yes Global Health
Health Data Science
Translational and Implementation Research
Infectious Disease		 Data science;
Modelling;
Policy;
Infectious diseases;
PCR
Rajko Reljic &
Graham Bothamley		 Antibody and aptamer approach to diagnosis of TB based on secreted proteins of Mycobacterium tuberculosis Yes Translational and Implementation Research
Infectious Disease		 Tuberculosis;
Diagnosis;
Serology;
Aptamers;
Latent infection
Elena Sviderskaya &
Yuri Korchev &
Kenneth Laing		 A new approach to understanding cancer cell heterogeneity No Translational and Implementation Research Cancer;
Cell biology;
Molecular biology;
Single cell gene expression;
Nano-biosensors;
High-resolution microscopy
Cally Tann &
Kirsty Le Doare &
Eric Ohuma &
Professor Joy Lawn		 Intrapartum-related neonatal encephalopathy in Africa: Defining burden, risk and outcomes Yes Global Health
Health Data Science
Translational and Implementation Research
Infectious Disease		 Newborn;
Neonatal encephalopathy;
Risk score;
Global estimates
Laith Yakob &
Timothy Planche		 Modelling Clostridium difficile vaccination strategy for the UK Yes Global Health
Health Data Science
Translational and Implementation Research
Infectious Disease		 Mathematical modelling;
Computational biology;
Infectious diseases;
Epidemiology;
Vaccination;
C. difficile

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