Potential Projects: Translational and Implementation Research
2023-24 MRC LID Studentships – potential projects under the Translational & Implementation Research theme.
| Supervisors | Project Title | Cross Institutional Supervision | Theme/s | Keywords |
|---|---|---|---|---|
| Angeliki Asimaki & Elijah Behr & Mark Specterman | Molecular distinction between arrhythmogenic cardiomyopathy and Brugada syndrome | No | Translational and Implementation Research | Magnetic Resonance Imaging, Quantitative Imaging, Quasi-Diffusion Imaging, Neuroimaging, Diffusion Dynamical Modelling, Tissue Microstructural Modelling |
| Thomas Barrick & Matt Hall & Philip Benjamin | Development of clinically specific tissue microstructural biomarkers from quasi-diffusion imaging | No | Translational and Implementation Research | Magnetic Resonance Imaging; Quantitative Imaging; Quasi-Diffusion Imaging; Neuroimaging; Diffusion Dynamical Modelling; Tissue Microstructural Modelling |
| Amaya Bustinduy & Sanjeev Krishna & Bonnie Webster | Development, implementation and assessment of isothermal point-of-care molecular diagnostics for both Female Genital Schistosomiasis and Human Papillomavirus | Yes | Translational & Implementation Research; Global Health; Infectious Disease | Isothermal diagnostics; multiplex, neglected tropical diseases; schistosomiasis; human papillomavirus |
| Christopher Carroll & Alan Pittman | Development of a transgenic mouse model for preclinical studies of therapeutic testing of mitochondrial disorders | No | Translational & Implementation Research | Omics; Metabolism; Inherited metabolic disease; Transgenics |
| Franklyn Howe & Thomas Barrick & Philip Benjamin | MRI tractomics of glial brain tumours | No | Translational & Implementation Research | Magnetic resonance imaging (MRI), brain tumour; machine learning; Quasi-Diffusion Imaging (QDI) |
| Gwen Knight & Jodi Lindsay | Antimicrobial Resistance Diversity: quantification, evolution, and importance for public health | Yes | Infectious Disease; Health Data Science; Global Health; Translational & Implementation Research | Antimicrobial resistance; mathematical modelling; MRSA; resistance diversity; intervention impact |
| Julian Ma & Audrey Teh | Engineering monoclonal secretory antibodies for mucosal immunotherapy | No | Infectious Disease; Translational & Implementation Research; Global Health | Antibody engineering; mucosal immunotherapy; molecular farming; passive immunisation |
| Nidhi Sofat & Anissa Chikh & Joseph Westaby | Understanding the mechanisms of pain and tissue damage induced by bone marrow lesions in osteoarthritis | No | Translational and Implementation Research | Pain; Neurobiology; Arthritis; Bone; Cartilage; Signalling |
| Elena Sviderskaya & Yuri Korchev & Kenneth Laing | A new approach to understanding cancer cell heterogeneity | No | Translational and Implementation Research | Cancer; Cell biology; Molecular biology; Single cell gene expression; Nano-biosensors; High-resolution microscopy |