Potential Projects: Translational and Implementation Research
2023-24 MRC LID Studentships – potential projects under the Translational & Implementation Research theme.
Applicants should note that this list is incomplete. Additional projects may be added until the end of November 2022.
|Supervisors||Project Title||Cross Institutional Supervision||Theme/s||Keywords|
|Angeliki Asimaki & Elijah Behr & Mark Specterman||Molecular distinction between arrhythmogenic cardiomyopathy and Brugada syndrome||No||Translational and Implementation Research||Magnetic Resonance Imaging, Quantitative Imaging, Quasi-Diffusion Imaging, Neuroimaging, Diffusion Dynamical Modelling, Tissue Microstructural Modelling|
|Thomas Barrick & Matt Hall & Philip Benjamin||Development of clinically specific tissue microstructural biomarkers from quasi-diffusion imaging||No||Translational and Implementation Research||Magnetic Resonance Imaging; Quantitative Imaging; Quasi-Diffusion Imaging; Neuroimaging; Diffusion Dynamical Modelling; Tissue Microstructural Modelling|
|Christopher Carroll & Alan Pittman||Development of a transgenic mouse model for preclinical studies of therapeutic testing of mitochondrial disorders||No||Translational & Implementation Research||Omics; Metabolism; Inherited metabolic disease; Transgenics|
|Franklyn Howe & Thomas Barrick & Philip Benjamin||MRI tractomics of glial brain tumours||No||Translational & Implementation Research||Magnetic resonance imaging (MRI), brain tumour; machine learning; Quasi-Diffusion Imaging (QDI)|
|Gwen Knight & Jodi Lindsay||Antimicrobial Resistance Diversity: quantification, evolution, and importance for public health||Yes||Infectious Disease; Health Data Science; Global Health; Translational & Implementation Research||Antimicrobial resistance; mathematical modelling; MRSA; resistance diversity; intervention impact|
|Julian Ma & Audrey Teh||Engineering monoclonal secretory antibodies for mucosal immunotherapy||No||Infectious Disease; Translational & Implementation Research; Global Health||Antibody engineering; mucosal immunotherapy; molecular farming; passive immunisation|
|Nidhi Sofat & Anissa Chikh & Joseph Westaby||Understanding the mechanisms of pain and tissue damage induced by bone marrow lesions in osteoarthritis||No||Translational and Implementation Research||Pain; Neurobiology; Arthritis; Bone; Cartilage; Signalling|
|Elena Sviderskaya & Yuri Korchev & Kenneth Laing||A new approach to understanding cancer cell heterogeneity||No||Translational and Implementation Research||Cancer; Cell biology; Molecular biology; Single cell gene expression; Nano-biosensors; High-resolution microscopy|