Potential projects
| Supervisors | Project Title | Cross Institutional Supervision | Theme/s | Keywords |
|---|---|---|---|---|
| Angeliki Asimaki & Elijah Behr & Mark Specterman | Molecular distinction between arrhythmogenic cardiomyopathy and Brugada syndrome | No | Translational and Implementation Research | Magnetic Resonance Imaging, Quantitative Imaging, Quasi-Diffusion Imaging, Neuroimaging, Diffusion Dynamical Modelling, Tissue Microstructural Modelling |
| Thomas Barrick & Matt Hall & Philip Benjamin | Development of clinically specific tissue microstructural biomarkers from quasi-diffusion imaging | No | Translational and Implementation Research | Magnetic Resonance Imaging; Quantitative Imaging; Quasi-Diffusion Imaging; Neuroimaging; Diffusion Dynamical Modelling; Tissue Microstructural Modelling |
| Amiya Bhatia & Daniel Carter & Karen Devries | How do childhood contexts affect violence against young people as they grow up? A quantitative, longitudinal and intersectional analysis of cohort data in Uganda | No | Global Health; Health Data Science | Social epidemiology; violence against children; causal inference; intersectionality; inequality |
| Amaya Bustinduy & Sanjeev Krishna & Bonnie Webster | Development, implementation and assessment of isothermal point-of-care molecular diagnostics for both Female Genital Schistosomiasis and Human Papillomavirus | Yes | Translational & Implementation Research; Global Health; Infectious Disease | Isothermal diagnostics; multiplex, neglected tropical diseases; schistosomiasis; human papillomavirus |
| Helena Carreira & Harriet Forbes & Krishnan Bhaskaran | Severe infection outcomes among cancer survivors in the UK | No | Health Data Science | Electronic health records; Cancer; Infections; Outcomes research |
| Christopher Carroll & Alan Pittman | Development of a transgenic mouse model for preclinical studies of therapeutic testing of mitochondrial disorders | No | Translational & Implementation Research | Omics; Metabolism; Inherited metabolic disease; Transgenics |
| Rosalind Eggo & Graham Medley | Modelling the disorganised ecology of post-pandemic respiratory viruses | No | Infectious Disease; Health Data Science | Mathematical modelling; Epidemiology; Respiratory viruses; Methodological novelty |
| Harriet Forbes & Helena Carreira & Krishnan Bhaskaran | Exploring long-term health outcomes among cancer survivors | No | Health Data Science | EHR data; cancer; statistics; mental health; cognition; quality of life |
| Jon Friedland & Deborah Chong | The role of platelet-fibroblast interactions in the pathology of pulmonary tuberculosis | No | Infectious Disease; Global Health | Tuberculosis; Innate immunity; Fibroblasts; Matrix metalloproteinases (MMPs); Platelets |
| Giorgia Gon & Sarah Whitmee & Rosemary Green | Social norms for climate change transformation | No | Global Health | Social norms; climate change transformation |
| Ozan Gundogdu & Brendan Wren | Campylobacter pathogenesis: the Unfolded Protein Response (UPR), inflammation and human disease | No | Infectious Disease; Global Health | Campylobacter, Gastroenteritis; inflammation; Unfolded Protein Response (UPR) |
| Sally Hargreaves & Julia Pescarini & Nuria Sanchez Clemente | Migrant health in children and young people in Europe: An analysis of Europe-wide routine datasets | Yes | Global Health | Migrant; children; young people; infectious diseases; sexual health; screening |
| Franklyn Howe & Thomas Barrick & Philip Benjamin | MRI tractomics of glial brain tumours | No | Translational & Implementation Research | Magnetic resonance imaging (MRI), brain tumour; machine learning; Quasi-Diffusion Imaging (QDI) |
| Gwen Knight & Jodi Lindsay | Antimicrobial Resistance Diversity: quantification, evolution, and importance for public health | Yes | Infectious Disease; Health Data Science; Global Health; Translational & Implementation Research | Antimicrobial resistance; mathematical modelling; MRSA; resistance diversity; intervention impact |
| Alex Lewin & Ruth Keogh & Sinead Langan | Causal mediation with time-updated variables in Survival analysis, with application to mediation analysis of the atopic dermatitis – cardiovascular disease association | No | Health Data Science | Causal inference; survival analysis; Bayesian methods; imputation |
| Julian Ma & Audrey Teh | Engineering monoclonal secretory antibodies for mucosal immunotherapy | No | Infectious Disease; Translational & Implementation Research; Global Health | Antibody engineering; mucosal immunotherapy; molecular farming; passive immunisation |
| Finn McQuaid & Gwen Knight | Comparing drug-resistant tuberculosis empirical treatment choices | No | Infectious Disease; Global Health; Health Data Science | Tuberculosis; Drug-resistance; Modelling; Health Economics |
| Joan Morris & Joachim Tan & Ruth Keogh | Methods for combining aggregated electronic health records data, with application to European data on children with rare congenital anomalies | Yes | Health Data Science | Meta-analysis; Survival Analysis; R programming; Health Care Data |
| Lucy Pembrey & Phil Cooper & Karin Van Veldhoven | Defining new asthma phenotypes using high dimensional data | Yes | Health Data Science; Global Health | Big data; Biomarkers; Asthma; Microbiome; Epigenomics |
| Chrissy Roberts & Amaya Bustinduy | Data science platforms for enhanced analytics and monitoring of female genital schistosomiasis and related health impacts | No | Health Data Science; Infectious Disease; Global Health | Machine Learning; Technology; Female Genital Schistosomiasis; Mixed Methods; Programming; Sexual and Reproductive health |
| Alicja Rudnicka & Alex Lewin & Christopher Owen | AI methodology for investigating age-related cognitive changes and retinal imaging | Yes | Health Data Science | Big data; Bayesian modelling; Machine learning; Spatial modelling |
| Anoop Shah & Poppy Mallinson & Alex Lewin | Applying deep learning to cardiac imaging to understand the pathology of premature heart disease in South Asian populations | No | Health Data Science; Global Health | Cardiac pathology; echocardiography; imaging; deep learning; statistics; disease mechanisms; India |
| Nidhi Sofat & Anissa Chikh & Joseph Westaby | Understanding the mechanisms of pain and tissue damage induced by bone marrow lesions in osteoarthritis | No | Translational and Implementation Research | Pain; Neurobiology; Arthritis; Bone; Cartilage; Signalling |
| Laura Southgate & Alan Pittman | Navigating the diagnostic odyssey of inherited vascular disease | No | Health Data Science | Bioinformatics; Genomics; Rare disease; Vascular disorders |
| Henry Staines & Elisabetta Groppelli | Development and evaluation of novel point-of-need cervical cancer screening devices to improve women’s health in low resource settings | No | Infectious Disease; Global Health | Molecular biology; PCR; Diagnostics; Infectious diseases; Cervical cancer |
| Henry Staines & Kirsty Le Doare & Elisabetta Groppelli | Impact of climate change on human health: detection of known and emerging mosquito-transmitted arboviruses in East Africa | No | Infectious Disease; Global Health | Molecular virology; Diagnostic development; Climate change impact on human health |
| Elena Sviderskaya & Yuri Korchev & Kenneth Laing | A new approach to understanding cancer cell heterogeneity | No | Translational and Implementation Research | Cancer; Cell biology; Molecular biology; Single cell gene expression; Nano-biosensors; High-resolution microscopy |
| John Tazare & Elizabeth Williamson | Faking it: exploring how to generate synthetic electronic health record data | No | Health Data Science | Electronic health records; machine learning; synthetic data |
| Elizabeth Williamson & Neil Pearce | Designing optimal rapid data collection strategies to maximise the utility of routinely collected health data for predicting risk of death from an emerging infectious disease | No | Health Data Science; Infectious Disease | Infectious disease; risk prediction; electronic health records; statistical methodology |
| Kevin Wing & John Tazare & Charlotte Warren-Gash | Improving the ability to study epilepsy in big data | No | Health Data Science | Epilepsy; electronic health records; case classification; trial replication |
| Angel Wong & Charlotte Warren-Gash | Evaluate and address the impact of COVID-19 lockdown on electronic health records in causal modelling research | No | Health Data Science | Electronic health records; pharmacoepidemiology; antibiotics; antipsychotics; COVID-19; quantitative bias analysis |