Potential projects

Applicants, please note: This list of all available 2023-24 MRC LID Studentships projects is incomplete. We anticipate projects will continue to be added to it until the end of November 2022.

Supervisors Project Title Cross Institutional Supervision Theme/s Keywords
Angeliki Asimaki & Elijah Behr & Mark Specterman Molecular distinction between arrhythmogenic cardiomyopathy and Brugada syndrome No Translational and Implementation Research Magnetic Resonance Imaging, Quantitative Imaging, Quasi-Diffusion Imaging, Neuroimaging, Diffusion Dynamical Modelling, Tissue Microstructural Modelling
Thomas Barrick & Matt Hall & Philip Benjamin Development of clinically specific tissue microstructural biomarkers from quasi-diffusion imaging No Translational and Implementation Research Magnetic Resonance Imaging; Quantitative Imaging; Quasi-Diffusion Imaging; Neuroimaging; Diffusion Dynamical Modelling; Tissue Microstructural Modelling
Amiya Bhatia & Daniel Carter & Karen Devries How do childhood contexts affect violence against young people as they grow up? A quantitative, longitudinal and intersectional analysis of cohort data in Uganda No Global Health; Health Data Science Social epidemiology; violence against children; causal inference; intersectionality; inequality
Helena Carreira & Harriet Forbes & Krishnan Bhaskaran Severe infection outcomes among cancer survivors in the UK No Health Data Science Electronic health records; Cancer; Infections; Outcomes research
Christopher Carroll & Alan Pittman Development of a transgenic mouse model for preclinical studies of therapeutic testing of mitochondrial disorders No Translational & Implementation Research Omics; Metabolism; Inherited metabolic disease; Transgenics
Rosalind Eggo & Graham Medley Modelling the disorganised ecology of post-pandemic respiratory viruses No Infectious Disease; Health Data Science Mathematical modelling; Epidemiology; Respiratory viruses; Methodological novelty
Harriet Forbes & Helena Carreira & Krishnan Bhaskaran Exploring long-term health outcomes among cancer survivors No Health Data Science EHR data; cancer; statistics; mental health; cognition; quality of life
Jon Friedland & Deborah Chong The role of platelet-fibroblast interactions in the pathology of pulmonary tuberculosis No Infectious Disease; Global Health Tuberculosis; Innate immunity; Fibroblasts; Matrix metalloproteinases (MMPs); Platelets
Giorgia Gon & Sarah Whitmee & Rosemary Green Social norms for climate change transformation No Global Health Social norms; climate change transformation
Ozan Gundogdu & Brendan Wren Campylobacter pathogenesis: the Unfolded Protein Response (UPR), inflammation and human disease No Infectious Disease; Global Health Campylobacter, Gastroenteritis; inflammation; Unfolded Protein Response (UPR)
Sally Hargreaves & Julia Pescarini & Nuria Sanchez Clemente Migrant health in children and young people in Europe: An analysis of Europe-wide routine datasets Yes Global Health Migrant; children; young people; infectious diseases; sexual health; screening
Franklyn Howe & Thomas Barrick & Philip Benjamin MRI tractomics of glial brain tumours No Translational & Implementation Research Magnetic resonance imaging (MRI), brain tumour; machine learning; Quasi-Diffusion Imaging (QDI)
Gwen Knight & Jodi Lindsay Antimicrobial Resistance Diversity: quantification, evolution, and importance for public health Yes Infectious Disease; Health Data Science; Global Health; Translational & Implementation Research Antimicrobial resistance; mathematical modelling; MRSA; resistance diversity; intervention impact
Alex Lewin & Ruth Keogh & Sinead Langan Causal mediation with time-updated variables in Survival analysis, with application to mediation analysis of the atopic dermatitis – cardiovascular disease association No Health Data Science Causal inference; survival analysis; Bayesian methods; imputation
Julian Ma & Audrey Teh Engineering monoclonal secretory antibodies for mucosal immunotherapy No Infectious Disease; Translational & Implementation Research; Global Health Antibody engineering; mucosal immunotherapy; molecular farming; passive immunisation
Finn McQuaid & Gwen Knight Comparing drug-resistant tuberculosis empirical treatment choices No Infectious Disease; Global Health; Health Data Science Tuberculosis; Drug-resistance; Modelling; Health Economics
Joan Morris & Joachim Tan & Ruth Keogh Methods for combining aggregated electronic health records data, with application to European data on children with rare congenital anomalies Yes Health Data Science Meta-analysis; Survival Analysis; R programming; Health Care Data
Lucy Pembrey & Phil Cooper & Karin Van Veldhoven Defining new asthma phenotypes using high dimensional data Yes Health Data Science; Global Health Big data; Biomarkers; Asthma; Microbiome; Epigenomics
Alicja Rudnicka & Alex Lewin & Christopher Owen AI methodology for investigating age-related cognitive changes and retinal imaging Yes Health Data Science Big data; Bayesian modelling; Machine learning; Spatial modelling
Anoop Shah & Poppy Mallinson & Alex Lewin Applying deep learning to cardiac imaging to understand the pathology of premature heart disease in South Asian populations No Health Data Science; Global Health Cardiac pathology; echocardiography; imaging; deep learning; statistics; disease mechanisms; India
Nidhi Sofat & Anissa Chikh & Joseph Westaby Understanding the mechanisms of pain and tissue damage induced by bone marrow lesions in osteoarthritis No Translational and Implementation Research Pain; Neurobiology; Arthritis; Bone; Cartilage; Signalling
Laura Southgate & Alan Pittman Navigating the diagnostic odyssey of inherited vascular disease No Health Data Science Bioinformatics; Genomics; Rare disease; Vascular disorders
Henry Staines & Elisabetta Groppelli Development and evaluation of novel point-of-need cervical cancer screening devices to improve women’s health in low resource settings No Infectious Disease; Global Health Molecular biology; PCR; Diagnostics; Infectious diseases; Cervical cancer
Henry Staines & Kirsty Le Doare & Elisabetta Groppelli Impact of climate change on human health: detection of known and emerging mosquito-transmitted arboviruses in East Africa No Infectious Disease; Global Health Molecular virology; Diagnostic development; Climate change impact on human health
Elena Sviderskaya & Yuri Korchev & Kenneth Laing A new approach to understanding cancer cell heterogeneity No Translational and Implementation Research Cancer; Cell biology; Molecular biology; Single cell gene expression; Nano-biosensors; High-resolution microscopy
John Tazare & Elizabeth Williamson Faking it: exploring how to generate synthetic electronic health record data No Health Data Science Electronic health records; machine learning; synthetic data
Elizabeth Williamson & Neil Pearce Designing optimal rapid data collection strategies to maximise the utility of routinely collected health data for predicting risk of death from an emerging infectious disease No Health Data Science; Infectious Disease Infectious disease; risk prediction; electronic health records; statistical methodology
Kevin Wing & John Tazare & Charlotte Warren-Gash Improving the ability to study epilepsy in big data No Health Data Science Epilepsy; electronic health records; case classification; trial replication
Angel Wong & Charlotte Warren-Gash Evaluate and address the impact of COVID-19 lockdown on electronic health records in causal modelling research No Health Data Science Electronic health records; pharmacoepidemiology; antibiotics; antipsychotics; COVID-19; quantitative bias analysis

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